Spalding Lab
Laboratory of Professor Kirsty L. Spalding, Karolinska Institutet
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In short
In short
The research of Professor Kirsty Spalding focuses on properties of human adipose tissue, with particular attention to adipocyte biology. Basic functions, such as adipocyte lipid and cell turnover, adipocyte cell biology, adipocyte responses to obesity and hyperinsulinemia, and cellular heterogeneity are investigated. The ultimate aim the Spalding lab has, is to better understand the contributions of adipocytes to health and pathology. The Spalding lab is embedded in Karolinska Institutet and the department of Cellular and Molecular Biology.
News
News
New paper on protein normalization using total protein for western blot analysis of human adipocytes
New paper on protein normalization using total protein for western blot analysis of human adipocytes
Monday the 1st of September 2024
Leo Westerberg, Benjamin Dedic, Kirsty Spalding, and colleagues have published a study introducing total protein normalization as a more reliable method for western blot analysis in human adipocytes. Compared to traditional housekeeping proteins, total protein normalization showed lower signal variability and reduced intra- and inter-individual differences, making it a superior reference for protein quantification. The full article can be read here.
New paper on senescence detection using reflected light
New paper on senescence detection using reflected light
Tuesday the 13th of August 2024
Benjamin Dedic, Leo Westerberg, Andrea Mosqueda Solís, Kirsty Spalding and collaborators have recently published a research article on senescence detection using reflected light. In this paper they describe how senescence-associated beta-galactosidase can be accurately measured using confocal microscopy. In addition this staining can now be paired with antibody labeling. Combined this unlocks new research possibilities for understanding cellular senescence. The article can be read here.
We are hiring a permanent or fixed term research specialist in computational and/or cell biology
We are hiring a permanent or fixed term research specialist in computational and/or cell biology
Tuesday the 6th of February 2024
If you have an interest in fat and a background in cell biology or computational biology, and would like to work with a team focused on understanding how obesity-associated adipocyte dysfunction contributes to disease, then we have a perfect position for you. You can read more in the detailed description below - or apply through the following links. Applicants who are eligible are encouraged to apply for both positions (fixed term and permanent).
Last application date
29.Feb.2024 11:59 PM CET
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