PEOPLE
GROUP LEADER
KIRSTY SPALDING
Originally from Australia, I completed my PhD in the field of neuroscience at the University of Western Australia. This was followed by postdoctoral studies at the Karolinska Institute, Sweden, where I switched from studying neuronal cell death to neuronal birth. During the later stages of my postdoctoral period I started a side project looking at fat cell turnover in human adipose tissue. This project developed in to several more projects and now the major interest of my research group is fat and the healthy and pathological function of mature human fat cells.
Contact: kirsty.spalding@ki.se
LABORATORY ENGINEER & MANAGER
LENA APPELSVED
I have a Bachelor of Molecular Biology and Biotechnology at KI. I have been working in the Spalding group as a lab manager since 2012. Between 1993 and 2012 I was working as a research scientist at AstraZeneca R&D, CNS and Pain. I have 3 years experience at a Clinical Immunology lab at Huddinge hospital as a laboratory technician. I have many administrative tasks in the group, but also contribute to various scientific project.
Contact: lena.appelsved@ki.se
POSTDOCTORAL FELLOWS
ESTHER WAN
I completed my PhD in epigenetics in Hong Kong. I am interested in adipocyte senescence and the potential epigenetic mechanisms governing the process.
Contact: esther.wan@ki.se
JEREMY DUFAU
After completing my PhD in cell biology exploring new components of TGFβ signaling in adipocyte, I joined Kirsty Spalding’s group. Here my post-doctoral research focuses on the alterations of signaling pathways leading to the establishment of adipocyte senescence
Contact: jeremy.dufau@ki.se
PhD STUDENTS
BENJAMIN DEDIC
After two years of delving into stem cell-derived pancreatic cells as an Institutional Fellow at Harvard University, my focus has shifted to insulin signaling in adipose tissue.
Contact: benjamin.dedic@ki.se
NIELS KRÄMER
After completing a master’s degree in medical epigenomics at the Radboud University, I am currently working as a doctoral student in Kirsty’s group. Here I study the browning potential of mature white adipocytes using fluorescence microscopy, qPCR and other techniques from molecular biology.
Contact: niels.kramer@ki.se
RESEARCH ASSISTANT
LEO WESTERBERG
I have a master’s degree in molecular biology from Stockholm university and am currently working as a research assistant in Kirsty Spalding’s group. I previously did my thesis project here wherein I tried to understand why adipocytes in the omental depot have lower levels of senescence than adipocytes in the subcutaneous depot, within the same individual. Now I work as a research assistant, assisting in different projects.
Contact: leo.westerberg@ki.se